That's a really important question to bring up with a nephrologist before starting anything new. An eGFR of 23 means the kidneys are working at a fairly reduced level (Stage 4 kidney disease), which affects how medications are processed by the body.
Jardiance (empagliflozin) is generally not recommended when eGFR falls below Show Full Answer
That's a really important question to bring up with a nephrologist before starting anything new. An eGFR of 23 means the kidneys are working at a fairly reduced level (Stage 4 kidney disease), which affects how medications are processed by the body.
Jardiance (empagliflozin) is generally not recommended when eGFR falls below 20–25, depending on the specific guidelines and the reason it's being prescribed. At an eGFR of 23, there are a few key concerns:
- The kidneys may not be able to clear the medication effectively
- The drug works partly through the kidneys, so its effectiveness is reduced at lower eGFR levels
- There is a higher risk of side effects, including dehydration and kidney stress
This doesn't mean it's automatically off the table — some doctors may still consider it in certain situations — but it requires very careful evaluation.
The most important step is to have an open conversation with a nephrologist or prescribing doctor who knows the full health picture. They can weigh the potential benefits against the risks at this specific eGFR level and make the safest recommendation.
May 30
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